Is it true that taking performance enhancing drugs and steroids is “just part of the game (of baseball)” as Tony Bosch of Biogensis expressed in 60 MinutesJanuary 12, 2014 ?
If there is, there’s also a rich history (and industry built up) to ban, monitor and characterize the influence of drugs in human performance, post-mortem analysis and forensic toxicology. Its a matter of public safety, and not reserved for athletes alone. Some interesting facts for the record:
The World Anti-Doping Agency (WADA), founded in 1999, with laboratories worldwide has banned the use of steroids for athletic purposes as they are “controlled substances”. A dose as small as a few millionth of a gram (microgram) can have a significant effect on our bodies, reports Michael Tinnesand in ChemMatters (Dec 2011) at www.acs.org/chemmatters.
Numerous U.S. state agencies and organizations including the Texas Dept of Public Safety have monitored prescription drugs since 1982 including cocaine, morphine, Oxycodone, Lyrica and other drugs including anabolic steroids.
According to an American Chemical Society (ACS) report, steroid hormones were invented in 1944 at Syntex, S.A., (Mexico). Later, production of testosterone and other steroid hormones were manufactured. (See The Marker Degradation” and the Creation of the Mexican Steroid Hormone Industry 1938-1945)..
According to an article by KD Fitch (July 2012), “androgenic-anabolic steroids (AAS) are the most frequent category of prohibited substances detected in the urine of athletes both globally and at the last two Summer Olympic Games.
Methods to detect AAS have evolved gradually over the years. Before MS detection systems became widely available and effective, the ability to detect metabolites was not easy.
There’s another historical fact:
The LDTD technology has been adopted by a number of national and regional laboratories. One of it’s users:
“We have used the Phytronix LDTD sources for several years, and have reported out over a 1,000,000 combined tests on LDTD/MS-MS instruments, and of course have submitted many proficiency samples with never an error…. it made a 16 hour run by LC decrease to a 15 minute run for 96 samples, and greatly decreased sample volumes required, so fewer QNS samples ….”
See for yourself – a number of application notes and posters are available for perusal (and download) at Clinical and Toxicology App Notes
See for Yourself*
Fast and Selective Quantifcation of Testosterone in Plasma using LDTD-QTrap 5500 SelexION is just one of a number of app notes in the Clinical and Toxicology sections at LDTD App Notes in Urine, Oral, Hair, Blood Matrices