The abundance of drug-related cases common today causes backlogs in forensic laboratories, which creates budgetary and policy problems and potentially compromises investigations. The laser diode thermal desorption (LDTD) source, coupled with MS, has demonstrated its applicability in analyzing samples in less than half of the time in other fields of study, and according to a recently-released evaluation by RTI International through NIJ funding, LDTD has the potential for use in screening and quantitation of biological samples in forensic laboratories.
RTI International is an independent, nonprofit institute that provides research, development, and technical services to government and commercial clients worldwide.
The LDTD was coupled with triple quadrupole (QQQ) MS for the high-throughput quantitative analysis of controlled substances and drug toxicology in forensic laboratories. One hundred eleven drugs of abuse were optimized in methanolic drug solutions (e.g., designer drugs, controlled substances).
Advantages of the LDTD system include:
- Quick installation
- Little instrument training
- No additional software requirement
- Ease of use
- Minimal maintenance
- Rapid sample analysis
- Minimal sample volume
- Lack of chromatographic solvents and consumables
- The ability to use across multiple MS platforms
Overall, LDTD has the potential for use in screening and quantitation of biological samples in forensic laboratories. Its ability to rapidly analyze a large number of samples in a short amount of time (~12 sec per sample) makes it ideal for high throughput forenisc labs — and labs competing with high throughput labs.
To read the entire report visit RTI LDTD Report and click on the link.
Overbrook will be with Phytronix at ASMS June 15-19 2014 – Baltimore, MD.
Visit with us at Booth #161 at the Baltimore Convention Center.
For latest application notes and posters, visit LDTD or Contact Us