Transforming Environmental Health Protection with High-Throughput Technologies
Recently, the EPA announced plans to test 10,000 compounds for toxicity using the same high throughput technologies which have revolutionized DNA sequencing and drug discovery. Using robotics which can screen thousands of compounds a week vs. a person who can precisely profile no more than 20 compounds a year, the Tox21 collaboration involving the EPA, NIH, and the FDA is well underway.
In addition to speed and scale, this high throughput approach offers significant cost savings and a reduction in the use of animals for toxicity testing purposes. This is just one of a dozen scientific initiatives underway according to the National Bioeconomy Blueprint.
Emerging Contaminants, Unpredictable Results, Emerging Technologies
Whether its detection of trace levels of explosives in groundwater and surface water contamination, or discovery of low levels of drugs like benzodiazepines ending up in our water supply affecting the behavior of fish, see C&EN (Feb. 18, 2013)., leading environmental labs are making the necessary investments in emerging technologies to prevent poisoning of humans and animals.
New technology at hand today
New technology that we distribute, the Laser Diode Thermal Desorption (LDTD) ion source, is the interface with a triple quadrupole mass spectrometer for high-throughput applications, like trace analysis, specifically with explosive compounds, and quantification of pesticides and pharmaceuticals in wastewater, and more.
New Extraction technologies
Another innovation we’ve recently seen is a relatively new extraction method used to extract pesticides from fruit and vegetables quickly, taking only a few short minutes to extract analytes from sample matrices.
Time Of Flight (TOF) Mass Spectrometry delivers sensitivity, selectivity and reliability
Environmental labs have continued to test emerging contaminants using the latest generation of HPLC/MS/MS, including Time of Flight (TOF) mass spectrometry which provides some of the lowest detection limits available for these emerging substances of concern (ESOC).
To learn more about the applications conducted by LDTD, check out LDTD or contact email@example.com., or 617-364-7683