Technology at the speed of light

If you looked at LDTD in the past but had reservations, it’s time to re-consider. Here’s why:

An LDTD-MS/MS configuration has been used in rigorous drugs of abuse and compliance testing and monitoring — including natural opiates and synthetic opiates.

Synthetic compounds like propoxyphene with its metabolite norpropoxyphene, and methadone with its metabolite EDDP for ultra-fast confirmation results have been run. LDTD has been used for both screening and confirmations …. and been handled up to 20 times faster in the sample prep phase, and up to 45 times faster in sample analysis …. using a LDTD- MS/MS configuration.

A lot has changed

Today, LDTD is being used as an integral part of a complete high throughput workflow for multiple compounds using LC-MS/MS. Faster confirmations are being done using LDTD. That’s because only the LDTD source uses an infrared laser to desorb samples that have been dried onto a stainless steel sample well in a 96-well plate (a 384-well plate version is also available). The limitations of traditional GC/MS analysis including lengthy run-time, risk of carryover and costs associated with derivatization and column replacement is evident.

I’m going to tell you a simple fact of forensic toxicology testing that you don’t hear every day

LDTD technology can help you expand into new geographies and market segments and lower costs dramatically . We’ll show you how.In a recent confirmation study of propoxyphene, a centrally acting narcotic analgesic agent, traditionally performed by LC-MS/MS or GC/MS analysis, was performed using LDTD with excellent linearity, no carryover and no interferences from common medications observed.

We’ll share our proven process

We work closely with our clients using a proven process throughout the evaluation, installation, method development and integration process. The LDTD increases productivity and contributes to growth, even as it bucks conventional approaches. It delivers high throughput analysis that creates value at a cost that’s surprisingly economical.

You can be more responsive to client requests for quick turnaround.

How fast?

Runtime for LCMSMS is 7 minutes and for LDTD-MSMS run time is 9 seconds.

Is it time to re-consider LDTD?For immediate consideration, or to re-visit LDTD now, and/or to learn the proven process for evaluation, please contact me at 617-364-7683 orrhalpern@overbrookscientific.com . You can also peruse dozens of app notes, presentations, new articles or watch the video at LDTD NowWe’re booked with installations from leading toxicology labs nationwide. There are no reservations when it comes to ultra fast sample introduction, screening and confirmations. Integrated to your mass spectrometer, the LDTD operation is easy, intuititve and requires no external software for file acquisition or data processing.We’re Overbrook Scientific, the only independent instrumentation provider of the Phytronix Technologies Laser Diode Thermal Desorption (LDTD) ion source.Overbrook Scientific, Inc. is a proud member of ASMS, ACS, AAPS, MBC and GBMSDG.

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A lot has changed

We’ll share our proven process

Runtime for LCMSMS is 7 minutes and for LDTD-MSMS run time is 9 seconds.